Cleanrooms demand a meticulously defined and executed cleaning regimen. SOPs for cleaning and sanitizing controlled environments are essential to ensure the continuous removal of viable and non-viable particulates while maintaining regulatory compliance and operational consistency.
Define cleaning frequencies and task sequences based on ISO classification
Select compatible cleanroom wipers, mops, and chemistries for various surfaces
Write clear, step-by-step SOPs that standardize procedures and minimize contamination risks
Incorporate validation, auditing, and visual inspection techniques to verify outcomes
“Having documented and scheduled cleaning that is conducted according to the SOP maintains the integrity of the controlled environment and decreases the risk of product contamination.”
Continue deepening your understanding of SOPs for controlled environments:
Chapter 1: Introduction to Writing Internal SOPs for Controlled Environments
Chapter 2: Optimizing Cleanroom Operations – SOPs for Gowning Protocols
Chapter 3: SOPs for Cleanroom Operator Requirements and Training